Pulmonary radioaerosol mucociliary clearance in primary ciliary dyskinesia
نویسندگان
چکیده
منابع مشابه
Pulmonary radioaerosol mucociliary clearance in primary ciliary dyskinesia.
Primary ciliary dyskinesia (PCD) is a genetic condition affecting one in 10 000–40 000 people from birth [1]; cilia fail to beat, and the airway clearance of mucus and debris is severely impaired. If untreated, this results in progressive lung infection leading to bronchiectasis and ultimately respiratory failure. Additionally, delayed diagnosis has implications for genetic counselling, appropr...
متن کاملClinical value of measurement of pulmonary radioaerosol mucociliary clearance in the work up of primary ciliary dyskinesia
BACKGROUND We aimed to evaluate and define the general clinical applicability and impact of pulmonary radioaerosol mucociliary clearance (PRMC) on the work up of patients suspected of having primary ciliary dyskinesia (PCD). In addition, we wanted to evaluate the accuracy of the reference values used in the PRMC test. METHODS Measurement of PRMC after inhalation of (99m)Tc-albumin colloid aer...
متن کاملPulmonary permeability in primary ciliary dyskinesia.
Pulmonary clearance (Pcl) of aerosolized 99mTc-DTPA was studied in fourteen patients with primary ciliary dyskinesia (PCD), (median age 23.5 yrs, range 12-44 yrs) and nine normal individuals (median age 23 yrs, range 18-27 yrs). All had never smoked. Regional Pcl was studied for arbitrarily defined central and peripheral regions of the lung using a gamma camera method, whilst total Pcl was stud...
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To assess mucociliary clearance in patients with tracheobronchoplasty, radioaerosol inhalation scanning was performed in 14 patients. The unilateral total lung clearance curve was fitted into two compartmental curves, fast and slow, by least-squares techniques in order to assess mucociliary clearance of the bronchial tree quantitatively. Half-time (T 1/2) of the curve resulting from the subtrac...
متن کاملPrimary ciliary dyskinesia.
Primary ciliary dyskinesia (PCD) is a rare genetic condition that affects the ciliary function of the respiratory tract, sperm tail, cilia of the embryonic node, and fallopian tube. The condition is characterized by impaired ciliary action, leading to recurrent lower-respiratory-tract infections, bronchiectasis, rhino-sinusitis, otitis media, impaired fertility in women, and infertility in men....
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2014
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00011814